Searchable abstracts of presentations at key conferences in endocrinology

ea0021p139 | Diabetes and metabolism | SFEBES2009

The effects of chloroquine on blood glucose and plasma insulin concentrations in male Sprague--Dawley rats

Musabayane Cephas , Murambiwa Pretty , Joosab Naseera , Masola Bubuya , Mukaratirwa Samson

Chloroquine, the commonly used in the treatment of malaria has been reported to elicit adverse effects such as hypoglycaemia through unknown mechanisms. In particular, literature to date has revealed that the effects of the drug on insulin concentrations remain obscure. Our investigation therefore focuses on establishing a possible mechanism of CHQ-induced hypoglycaemia with regards to its effects on plasma insulin concentrations. The purpose of this study was to investigate t...